Human papillomavirus review article

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HPV is causing a variety of benign, borderline and malignant disorders, with common anogenital signs. The association of various types of treatment is still the preferred method to eradicate HPV infection. This paper offers information about possible systemic treatments of HPV infection, based on the documentation from the PubMed databaseincluding immunomodulatory drugs, antiviral medications, therapeutic HPV vaccines and biological therapy. Keywords HPV, HPV systemic treatment, therapeutic vaccines, systemic immunomodulators, systemic antiviral drugs Rezumat Infecţia umană cu diferite genotipuri ale virusului papiloma uman HPV este una dintre cele mai frecvente infecţii virale cu transmitere sexuală.

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Language of Keywords: English; Romanian Abstract: Epidermodysplasia verruciformis EV is a rare genodermatosis, with unique susceptibility to chronic cutaneous infections involving specific Human Papilloma Virus types in the genus β. Clinically, lesions display polymorphism and consist of discrete or confluent, often red-brown papules verruca plana-like lesions distributed on the extremities, usually dorsal hands, face and neck. The diagnosis of EV is based on clinical, histopathological and molecular features.